{"id":409,"date":"2025-05-18T09:56:12","date_gmt":"2025-05-18T00:56:12","guid":{"rendered":"https:\/\/suzukawa-clinic.jp\/blog\/?p=409"},"modified":"2025-05-18T09:58:43","modified_gmt":"2025-05-18T00:58:43","slug":"%e8%80%81%e5%8c%96%e3%81%a8%e5%81%a5%e5%ba%b7%e5%af%bf%e5%91%bd","status":"publish","type":"post","link":"https:\/\/suzukawa-clinic.jp\/blog\/?p=409","title":{"rendered":"\u8001\u5316\u3068\u5065\u5eb7\u5bff\u547d"},"content":{"rendered":"\n<p>\u8001\u5316\/\u52a0\u9f62\u3068\u9ad8\u8840\u5727\u75c7\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5\u3068\u3044\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u75c5\u306b\u306f\u95a2\u9023\u6027\u304c\u3042\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u6709\u7121\u306f\u5065\u5eb7\u5bff\u547d\u306e\u9577\u77ed\u306b\u5f71\u97ff\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u8001\u5316\u306f\u907f\u3051\u3089\u308c\u306a\u3044\u3082\u306e\u3067\u3059\u304c\u5065\u5eb7\u5bff\u547d\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u500b\u3005\u306e\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u306f\u751f\u6d3b\u7fd2\u6163\u6539\u5584\u306b\u3088\u308a\u6291\u5236\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u540c\u3058\u6b74\u5e74\u9f62\u3067\u3042\u3063\u3066\u3082\u3001\u82e5\u3055\u3092\u4fdd\u3063\u3066\u3044\u308b\u65b9\u304c\u3044\u308b\u4e00\u65b9\u3067\u3001\u5e74\u9f62\u4ee5\u4e0a\u306b\u8001\u5316\u3057\u3066\u3044\u308b\u65b9\u304c\u3044\u308b\u3088\u3046\u306b\u3001\u66a6\u5e74\u9f62\u3068\u751f\u7269\u5b66\u7684\u5e74\u9f62\u306b\u306f\u30ae\u30e3\u30c3\u30d7\u304c\u307f\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u751f\u7269\u5b66\u7684\u5e74\u9f62\u3092\u77e5\u308b\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u65b9\u6cd5\u304c\u63d0\u5531\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001DNA\u30e1\u30c1\u30eb\u5316\uff08\u30a8\u30d4\u30b2\u30ce\u30e0\uff09\u60c5\u5831\u306b\u57fa\u3065\u304f\u751f\u7269\u5b66\u7684\u5e74\u9f62\u4e88\u6e2c\u30e2\u30c7\u30eb\uff08\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u30fb\u30af\u30ed\u30c3\u30af\uff09\u304c\u3001\u305d\u306e\u4fe1\u983c\u6027\u306e\u9ad8\u3055\u304b\u3089\u56fd\u5185\u5916\u3067\u8001\u5316\u7814\u7a76\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7885055\/\">The use of DNA methylation clock in aging research &#8211; PMC<\/a><\/p>\n\n\n\n<p>\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u30fb\u30af\u30ed\u30c3\u30af\u306f2013\u5e74\u4ee5\u964d\u76db\u3093\u306b\u8001\u5316\u7814\u7a76\u306b\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u304c\uff08\u7b2c\u4e00\u4e16\u4ee3\u30af\u30ed\u30c3\u30af\uff09\u3001\u305d\u306e\u5f8c\u5065\u5eb7\u30ea\u30b9\u30af\u3084\u751f\u7406\u7684\u72b6\u614b\u306e\u9055\u3044\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50CpG\u30b5\u30a4\u30c8\u306e\u30e1\u30c1\u30eb\u5316\u30d1\u30bf\u30fc\u30f3\u304b\u3089\u751f\u7269\u5b66\u7684\u5e74\u9f62\u304c\u63a8\u5b9a\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\uff08\u7b2c\u4e8c\u4e16\u4ee3\u30af\u30ed\u30c3\u30af\uff09\u3001\u3088\u308a\u9ad8\u3044\u7cbe\u5ea6\u3067\u52a0\u9f62\u6027\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306a\u3069\u3082\u8e0f\u307e\u3048\u305f\u751f\u7269\u5b66\u7684\u5e74\u9f62\u3092\u63a8\u5b9a\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u73fe\u5728\u3067\u306f\u3001\u30c0\u30cb\u30fc\u30c7\u30f3\u7814\u7a76\u306b\u3088\u308a\u5f97\u3089\u308c\u305f\u30c7\u30fc\u30bf\u5229\u7528\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u751f\u7269\u5b66\u7684\u5e74\u9f62\u306e\u307f\u306a\u3089\u305a\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u3082\u63a8\u5b9a\u3059\u308b\u7b2c\u4e09\u4e16\u4ee3\u30af\u30ed\u30c3\u30af\u304c\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35029144\/\">DunedinPACE, a DNA methylation biomarker of the pace of aging &#8211; PubMed<\/a><\/p>\n\n\n\n<p>\u30a8\u30d4\u30af\u30ed\u30c3\u30af<sup>\u00ae<\/sup>\u30c6\u30b9\u30c8\u306f\u3001\u7b2c\u4e8c\u4e16\u4ee3\u30af\u30ed\u30c3\u30af\u306ePhenoAge\u3092\u30d9\u30fc\u30b9\u306b\u65e5\u672c\u4eba\u30a8\u30d4\u30b2\u30ce\u30e0\u30c7\u30fc\u30bf\u3092\u5b66\u7fd2\u3055\u305b\u65e5\u672c\u4eba\u306b\u6700\u9069\u5316\u3057\u305f\u30af\u30ed\u30c3\u30af\u3067\u3001\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u3082\u8a55\u4fa1\u53ef\u80fd\u3067\u3059\u3002<a href=\"https:\/\/scholar.google.com\/scholar_lookup?journal=Mathematics&amp;title=Transfer%20elastic%20Net%20for%20developing%20epigenetic%20clocks%20for%20the%20Japanese%20population&amp;author=Y.%20Tomo&amp;author=R.%20Nakaki&amp;volume=12&amp;issue=17&amp;publication_year=2024&amp;pages=2716&amp;doi=10.3390\/math12172716&amp;\">Tomo: Transfer elastic Net for developing epigenetic&#8230; &#8211; Google Scholar<\/a><\/p>\n\n\n\n<p>\u30a8\u30d4\u30af\u30ed\u30c3\u30af<sup>\u00ae<\/sup>\u30c6\u30b9\u30c8\u3067\u306f\u3001\u5f97\u3089\u308c\u305f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30c3\u30af\u30b9\u60c5\u5831\u304b\u3089\u751f\u7269\u5b66\u7684\u5e74\u9f62\u3001\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u306e\u307f\u306a\u3089\u305a\u3001\u8001\u5316\u306b\u95a2\u9023\u3059\u308b\u904b\u52d5\u6a5f\u80fd\u3001\u547c\u5438\u80ba\u6d3b\u91cf\u3001\u30c6\u30ed\u30e1\u30a2\u9577\u3084\u8840\u4e2d\u30b7\u30b9\u30bf\u30c1\u30f3C\u30ec\u30d9\u30eb\u3001\u8840\u4e2d\u30ec\u30d7\u30c1\u30f3\u30ec\u30d9\u30eb\u3001\u8840\u4e2d\uff30\uff21\uff29\uff0d\uff11\u30ec\u30d9\u30eb\u3068\u3044\u3063\u305f\u52a0\u9f62\u6027\u75be\u60a3\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u3084\u3001\u55ab\u7159\u66b4\u9732\u30ec\u30d9\u30eb\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u66b4\u9732\u30ec\u30d9\u30eb\u3001\u30d5\u30ec\u30a4\u30eb\u30fb\u30ed\u30b3\u30e2\u30ea\u30b9\u30af\u3068\u3044\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u306b\u95a2\u9023\u3059\u308b\u5065\u5eb7\u6307\u6a19\u3092\u8a55\u4fa1\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36008412\/\">Methylation risk scores are associated with a collection of phenotypes within electronic health record systems &#8211; PubMed<\/a> <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC6173330\/\">DNA methylation age \u2013 environmental influences, health impacts, and its role in environmental epidemiology &#8211; PMC<\/a><\/p>\n\n\n\n<p>\u5065\u5eb7\u5bff\u547d\u3092\u5ef6\u4f38\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u73fe\u5728\u306e\u751f\u7269\u5b66\u7684\u5e74\u9f62\u3068\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u3001\u305d\u308c\u3089\u306b\u95a2\u9023\u3059\u308b\u5065\u5eb7\u6307\u6a19\u306e\u73fe\u72b6\u3092\u77e5\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u4eca\u5f8c\u3069\u306e\u3088\u3046\u306a\u751f\u6d3b\u7fd2\u6163\u3092\u3068\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\u304b\u30a2\u30af\u30b7\u30e7\u30f3\u30d7\u30e9\u30f3\u3092\u8003\u3048\u3001\u5b9f\u884c\u3059\u308b\u3053\u3068\u304c\u809d\u8981\u3067\u3059\u3002\u5b9a\u671f\u7684\u306a\u30a8\u30d4\u30af\u30ed\u30c3\u30af<sup>\u00ae<\/sup>\u30c6\u30b9\u30c8\u304b\u3089\u5f97\u3089\u308c\u308b\u60c5\u5831\u306f\u3001\u5065\u5eb7\u5bff\u547d\u5ef6\u4f38\u306e\u305f\u3081\u306e\uff30\uff24\uff23\uff21\u30b5\u30a4\u30af\u30eb\u3092\u56de\u3059\u4e00\u52a9\u306b\u306a\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u30a8\u30d4\u30af\u30ed\u30c3\u30af<sup>\u00ae<\/sup>\u30c6\u30b9\u30c8\u3000\u751f\u7269\u5b66\u7684\u5e74\u9f62\u691c\u67fb\u3000<a href=\"https:\/\/drive.google.com\/file\/d\/1yI6C4GJLKCS_IJPVFyjXCHkSA1WoTeU-\/view\">\u4e00\u822c\u5411\u3051_\u751f\u7269\u5b66\u7684\u5e74\u9f62\u691c\u67fb_\u30a8\u30d4\u30af\u30ed\u30c3\u30af\u30c6\u30b9\u30c8\u306e\u3054\u8aac\u660e.pdf &#8211; Google \u30c9\u30e9\u30a4\u30d6<\/a>\u3000<a href=\"https:\/\/www.nikkei.com\/article\/DGXZQOUD224CC0S5A120C2000000\/\">\u8001\u5316\u6642\u8a08\u306f\u5dfb\u304d\u623b\u305b\u308b\u3000\u4eba\u751f100\u5e74\u3001\u7d42\u6d3b\u3088\u308a\u300c\u8001\u6d3b\u300d &#8211; \u65e5\u672c\u7d4c\u6e08\u65b0\u805e<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u8001\u5316\/\u52a0\u9f62\u3068\u9ad8\u8840\u5727\u75c7\u3001\u8102\u8cea\u7570\u5e38\u75c7\u3001\u7cd6\u5c3f\u75c5\u3068\u3044\u3063\u305f\u751f\u6d3b\u7fd2\u6163\u75c5\u306b\u306f\u95a2\u9023\u6027\u304c\u3042\u308a\u3001\u751f\u6d3b\u7fd2\u6163\u75c5\u306e\u6709\u7121\u306f\u5065\u5eb7\u5bff\u547d\u306e\u9577\u77ed\u306b\u5f71\u97ff\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u8001\u5316\u306f\u907f\u3051\u3089\u308c\u306a\u3044\u3082\u306e\u3067\u3059\u304c\u5065\u5eb7\u5bff\u547d\u306b\u306f\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u500b\u3005\u306e\u8001\u5316\u30b9\u30d4\u30fc\u30c9\u306f\u751f\u6d3b\u7fd2 &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/suzukawa-clinic.jp\/blog\/?p=409\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;\u8001\u5316\u3068\u5065\u5eb7\u5bff\u547d&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[101,5,4],"tags":[],"class_list":["post-409","post","type-post","status-publish","format-standard","hentry","category-101","category-5","category-4"],"_links":{"self":[{"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts\/409"}],"collection":[{"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=409"}],"version-history":[{"count":15,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts\/409\/revisions"}],"predecessor-version":[{"id":424,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=\/wp\/v2\/posts\/409\/revisions\/424"}],"wp:attachment":[{"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=409"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=409"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/suzukawa-clinic.jp\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=409"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}